BDBM199089 US9221839, 1a
SMILES CN1C(=N)N[C@@]2(COC[C@@H]2S1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
InChI Key InChIKey=FEUVBQUAABZEJQ-YJBOKZPZSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 199089
Affinity DataKi: 491nM ΔG°: -8.74kcal/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a
time-resolved endpoint proteolysis assay that measures hydrolysis of the
QSY7-EISE...More data for this Ligand-Target Pair